Selective A2A adenosine receptor activation reduces skin pressure ulcer formation and inflammation
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چکیده
منابع مشابه
Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation.
Activation of A(2A) adenosine receptors (A(2A)-AR) by ATL-146e (formerly DWH-146e) prevents inflammatory cell activation and adhesion. Recurrent ischemia-reperfusion (I/R) of the skin results in pressure ulcer formation, a major clinical problem. ATL-146e was evaluated in a novel reproducible rat model of pressure ulcer. A 9-cm(2) region of dorsal rat skin was cyclically compressed at 50 mmHg u...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2001
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.2001.281.1.h67